Limestone has four biology labs for instruction and research. Limestone also has several well-equipped chemistry labs, which may be used to support biological related activities and courses. Hamrick Hall of Science is one of the many renovated historic buildings on campus and has wireless access throughout.
Three computer laboratories are also available for blended course instruction and student use in Limestone's science building, Hamrick Hall. All computers are equipped with commonly used software for word processing and spreadsheets as well as resources for improving the grammar and style of research papers to aid in research and data retrieval, access is also available to the Internet.